Liver failure is a serious liver disease with a high mortality rate and poor prognosis. Acute liver failure is the appearance of clinical syndromes such as hepatic encephalopathy and ascites of degree II or higher within 2 weeks, with a higher mortality rate; subacute liver failure is the appearance of liver failure syndromes such as jaundice, ascites and hepatic encephalopathy within 2 weeks to 6 months, with a relatively lower mortality rate than acute liver failure; slow plus acute liver failure is the sudden aggravation of chronic liver disease and the appearance of acute liver function loss, when slow plus acute liver failure occurs. Chronic liver failure is a progressive decompensation of liver function based on cirrhosis, with the development of hepatic encephalopathy, ascites and other syndromes. In the case of chronic liver failure, after the development of liver failure, the only effective treatment option is ultimately liver transplantation. Therefore, liver failure is a serious liver disease with a high morbidity and mortality rate, which can reach about 70%-80% overall.