Uremia may present in the early stages with symptoms such as nausea, vomiting, fatigue, insomnia, lack of concentration, and dyspnea. Uremia can lead to metabolite retention, imbalance of water-electrolyte and acid-base balance as well as the development of systemic diseases. In the early stage, patients may experience digestive symptoms such as nausea and vomiting due to the accumulation of toxins; renal anemia may cause fatigue, etc.; early neuromuscular system may cause insomnia and lack of concentration, etc.; and water and sodium retention may cause respiratory distress. Uremia may also appear in the early stage of other uncomfortable symptoms, it is recommended that patients go to the regular hospital in a timely manner, under the guidance of the doctor standardized treatment, so as not to delay the condition.