The most likely cause of a flesh dent on the face is a filiform wart or flat wart that results from a human papilloma virus infection. It is a superfluous growth on the skin that does not feel or itch, but is simply a small protrusion that can be felt or seen. It is possible to use freezing and ionization to eliminate it with immediate effect, together with recombinant human interferon gel to avoid recurrence of the condition. Immunomodulators such as BCG polysaccharide nucleic acid can be used intramuscularly for a two-month course of treatment. Some patients may not be particularly effective and can be treated with drugs such as oral isotretinoin.