Usually the pain will last for 1~2 hours after the stone enters into the ureter, or it may not be relieved and need lithotripsy or surgery to relieve. 1. Smaller diameter kidney stones usually do not cause pain, most of the severe pain is due to the stone falls into the ureter, causing ureteral spasm and resulting in renal colic. This kind of pain usually lasts 1~2 hours, with the stone on the ureter stimulation weakened, the pain can disappear. However, if the stone moves again, stimulation of the ureter resulting in renal colic will reappear, the need to promptly seek antispasmodic pain treatment. 2. If the stone is large, and the combination of infection, hydronephrosis caused by the pain, often can not be relieved on their own. Patients need to seek timely medical treatment, lithotripsy or surgical stone removal and other appropriate treatment, the pain can be relieved. It is recommended that patients who suffer from pain caused by kidney stones should go to regular hospitals in time to find out the cause of the disease and then undergo treatment, so as to avoid delaying the condition and leading to adverse consequences.