Gout can be caused by the following reasons: First, gout, the most common joint involved in gout is the big toe joint, which can cause pain in the big toe joint, accompanied by swelling and increased skin temperature, redness of the skin, and in severe cases, gout stone formation. Second, bacterial infection or tuberculosis infection, which can also appear in the joint of the big toe pain, can be accompanied by skin redness and swelling, then early blood tests and examination of the big toe x-ray, nuclear magnetic to early diagnosis. Third, aseptic inflammatory diseases, such as osteoarthritis and rheumatoid arthritis, can also cause pain in the big toe joint, which can be accompanied by swelling and deformity, so early diagnosis should be made by taking x-rays of the toe and blood tests.