The normal range of total bilirubin is 1.7 to 17.1 umol/L. 27.2 umol/L is not normal and is considered high. High total bilirubin may be due to physiological reasons, newborns can have physiological jaundice after birth, total bilirubin can be high, usually occurring in the first 2-3 days after birth, and return to normal in 7-10 days, usually no special discomfort can not be special treatment. High total bilirubin may also be due to pathological reasons, which can be divided into liver disease, hemolytic disease and biliary tract obstructive disease. Liver disease commonly includes viral hepatitis, drug liver injury, cirrhosis, etc.; hemolytic disease commonly includes autoimmune hemolytic anemia; and biliary tract obstructive disease commonly includes gallstones, cholangiocarcinoma, and cancer of pancreatic head, etc. These diseases should be treated according to their causes. These diseases should be treated for their causes. Bilirubin 27.2umol/L should go to the hospital, complete the examination under the guidance of the doctor according to the cause of the treatment.