After palliative resection surgery chemotherapy and radiotherapy for type B3 thymoma, some patients can still be operated, and the specific choice of treatment needs to follow the doctor’s advice. B3 thymoma belongs to highly malignant thymoma, patients who have undergone palliative surgery as well as chemotherapy and radiotherapy, indicating that the patient’s clinical stage is on the late side, and B3 thymoma in the middle or late stage is prone to recurrence or metastatic disease changes after treatment. Some patients may be given another surgery to remove the tumor if local recurrence occurs after treatment. For patients who have recurrence of B3 thymoma and then undergo surgery again, chemotherapy and radiotherapy are generally recommended to control the further development of the disease, and the patients should be closely followed up after the treatment to find out the progress of the disease in time so as to take treatment measures in time.