Closed-cell pimples have to be drained out in order to get better because they are caused by blockage of the follicular opening, which, if not drained out, leads to further deposition of oil and grease, resulting in further aggravation of acne. Closed-cell pimples, or acne, are caused by excessive sebum secretion and abnormal keratinization of the follicular opening, resulting in blockage of the pores by sebum plugs and poor drainage of oil. Failure to open the follicular pore can lead to further lipid deposition, resulting in localized infections and abnormal keratinization of the follicular ducts, leading to aggravation of acne and further development of inflammatory papules and nodules. There are many ways to promote the discharge of closed mouth acne, the common topical drugs are retinoic acid preparations, such as adapalene, which can regulate the abnormal keratinization of the follicular opening, dissolve lipids, and at the same time have a certain anti-inflammatory and antibacterial effect, to promote the discharge of acne. At the same time, chemical peels can be used to reduce facial oil, dissolve keratin, and promote the discharge of acne. If you have closed mouth acne should be timely to the hospital, follow the doctor’s instructions standardized treatment, to avoid further aggravation of the symptoms.