How much bitter almonds can be poisoned by eating

Whether or not bitter almonds can cause poisoning is related to the amount of bitter amygdalin and bitter amygdalinase contained in the almonds. Usually the more bitter the almond is, the more toxic it is. If an adult eats 20-60 bitter almonds and a child eats 10-20 bitter almonds by mistake, poisoning can occur to varying degrees and even lead to death. Bitter almond poisoning belongs to cyanogenic glycoside-containing plant poisoning, mainly because bitter almonds contain bitter amygdalin and bitter amygdalinase. Bitter amygdalin can be decomposed into hydrocyanic acid, benzaldehyde and glucose under the action of bitter amygdalinase when it meets water, so excessive consumption can induce hydrocyanic acid poisoning. The clinical manifestations of bitter almond poisoning are nausea, vomiting, fatigue, peripheral discomfort, as well as dizziness, headache, sleepiness or irritability in mild cases. In more severe cases, vomiting is frequent and accompanied by rapid breathing and heartbeat, cyanosis, twitching or tonicity of the limbs, resistance in the neck, and hyperactive knee reflexes. In severe cases, patients may exhibit confusion, dyspnea, dilated pupils and dull or even complete loss of light reflex, paroxysmal spasms or tonicity of the limbs, cardiac arrhythmias, and respiratory failure. Some patients will be accompanied by high fever and liver enlargement. Because this type of poisoning is extremely harmful and responds quickly, it is necessary to go to the hospital immediately for rescue treatment. The main clinical measures are emetic, gastric lavage, and diarrhea to promote the excretion of toxic substances from the body, injection of nitrite and sodium thiosulfate for detoxification treatment, and blood transfusion or blood exchange treatment if necessary.