1. Cough: The most common symptom of respiratory disease. It is often mistaken by us for a respiratory infection. If no improvement is seen after active anti-infection, cough suppression and other treatments, it is necessary to take a radiograph to rule out the possibility of the presence of a mass. 2, hemoptysis: hemoptysis is also more respiratory disease, generally appear intermittent, repeated hemoptysis, the patient is extremely likely to seek medical attention. Often a CT can be taken to get some hints for the next direction of management. The hematologic and vascular nature of the mass is quite rich and prone to partial tissue necrosis and hemoptysis, so this is a fairly important sign. However, many patients complain of hemoptysis due to bleeding gums, especially in the morning when they spit up secretions or gargle, while there will be no hemoptysis at other times. 3. Chest pain: According to statistics, 25%-50% of lung cancer patients will have the symptom of chest pain. The pain of lung cancer can be intermittent or continuous and increasingly severe because lung cancer has invaded the ribs, intercostal nerves, pleura and so on, which often indicates the progress of lung cancer. 4.Difficulty in breathing: There are many reasons for difficulty in breathing, the most common reasons are obstruction of trachea and bronchus, and pleural effusion caused by advanced tumor, etc. 5.Heartiness: If there is unexplained hoarseness, which cannot be relieved continuously, it may also be caused by tumor invading the laryngeal recurrent nerve. specific systemic cutaneous, neurological, and endocrine manifestations, and unilateral restricted croup or wet rales found on physical examination.