There are several ways to differentiate between herpes zoster and genital herpes: 1. Herpes zoster is mainly due to varicella-zoster virus infection, while genital herpes is mainly due to herpes simplex virus type 2 infection. 2. The site of onset, herpes zoster can travel along the peripheral nerves in any part of the body, with a unilateral band distribution and clustered distribution The first of these is a cluster of small blisters, blood blisters or pustules. In the clinical treatment, herpes zoster can be treated with oral mecobalamin capsules to nourish the nerves along with antiviral therapy, while genital herpes does not require such nerve-nourishing drugs.