Prevention of postherpetic neuralgia

  Herpes zoster is an acute viral infectious skin disease caused by varicella zoster virus, also known as “tangled waist fire dan”, “turn waist dragon”, commonly known as “snake dan”, “spider sores”. “spider sores”. The annual incidence of this disease is about 0.5%, and it is prone to occur in the elderly. Many patients have clinical symptoms of post-herpetic neuralgia, and early treatment is the key.  Treatment of herpes zoster should begin with adequate rest and avoid straining. Pharmacological treatment includes antiviral, analgesic, anti-inflammatory and prevention of complications. The disease is self-limiting, with a duration of about half a month in most cases, usually 2 to 3 weeks, and up to 3 to 4 weeks or more in older patients. In young adults, unless the lesions produce necrotic ulcers, there is usually no scarring. Recurrence is rare. Many patients develop clinical symptoms of posterior neuralgia, and early treatment is the key to preventing this symptom.  Antiviral Internal treatment is preferred to antiviral drugs such as acyclic guanosine. Early application (within 3 days of blister onset) significantly reduces the incidence of posterior neuralgia. Vanaciclovir, famciclovir, and penciclovir may also be used.  Note that there are adverse effects of cyclic guanosine, that more water should be consumed to prevent its deposition in the kidney, and that the dosage should be reduced in cases of renal dysfunction. In addition, the course of antiviral drugs is 7 to 14 days. If the blisters have subsided, it is pointless to continue using antiviral drugs.  Glucocorticoids Early application (within 3-5 days of onset) of glucocorticoids, such as prednisone 40-60 mg/day, taken at breakfast, can reduce the inflammatory response and pain. The duration of treatment is 1 week, and then the dosage is rapidly reduced to discontinuation within 1 to 2 weeks.  Note that hormones are not effective in shortening the duration of the disease and do not reduce the occurrence of posterior neuralgia. This drug must be used in combination with antiviral drugs. It should not be used in immunocompromised patients because it can cause a generalized skin rash and visceral herpes in immunocompromised patients.  Gabapentin This drug is an anticonvulsant drug and can effectively treat posterior neuralgia, which can be effective within 2 days of administration. Generally, the first dose of 100-300 mg/day is gradually increased to 3 times/day, and then increased by 100-300 mg every 3 days to a total of 1800-2400 mg/day, which can effectively treat posterior neuralgia. This drug can be used early in combination with antiviral drugs to prevent posterior neuralgia.  Chinese medicine To clear the heat and detoxify the blood and cool the sunset, you can use gentian diarrhea sunset soup plus reduction.  Other 1.Vitamin B1 100 mg, vitamin B12 500μg intramuscular injection, 1 time/day for 10 days, can help relieve neuritis.  2, topical therapies can be used for the treatment of furnace glycerin lotion, acyclic guanosine gel, etc. Anti-infective drugs are available for those with secondary infection.  3, physical therapy such as ultraviolet light, negative ion spray, far-infrared physical therapy, semiconductor laser, etc. can assist in relieving pain, accelerating the fading of lesions, promoting the absorption of inflammation and shortening the course of the disease.  4. For ocular lesions, herpes purification and antibiotic eye drops can be used, and ophthalmology consultation should be sought quickly to prevent corneal damage and blindness.  Tips The fundamental prevention of postherpetic neuralgia is to prevent the occurrence of herpes zoster, enhance the body’s defense ability, and avoid overexertion. Early diagnosis and prompt antiviral treatment are also key to preventing postherpetic neuralgia. Patients with herpes zoster should be isolated, especially from pregnant women, elderly people, immunocompromised people and infants.