In the clinic, yttrium 90 (90Y) can treat liver cancer. Yttrium 90 is a more ideal therapeutic radionuclide, mainly used for the preparation of therapeutic radiopharmaceuticals. Currently, 90Y-resin microspheres are available in China for the treatment of liver cancer, colorectal liver metastases and other liver malignancies. Through interventional technology, high-dose radioactive microspheres are delivered into the tumor via the hepatic artery, and the tumor is targeted with close-range high-dose radioactive irradiation to kill liver cancer cells. 90Y-Resin Microsphere Precision Therapy is a more advanced treatment method in the world, which has the advantages of no large incision, precision, minimally invasive and less side effects. Meanwhile, 90Y-Resin Microsphere Injection can be used alone or in combination with other comprehensive treatment modalities, such as biological, immune, and targeted, to further improve the therapeutic effect. It is recommended that liver cancer patients receive appropriate treatment modalities under the guidance of doctors.