High pressure 100mmHg low pressure 53mmHg is not normal, belongs to the hypotensive disease, physiological hypotensive disease does not need to be treated, pathologic hypotensive disease should actively treat the primary disease. High pressure is systolic pressure, the normal reference value range is 100-139mmHg, low pressure is diastolic pressure, the normal reference value range is 60-89mmHg, multiple measurements of systolic blood pressure is lower than 100mmHg or (and) diastolic blood pressure is lower than 60mmHg, is considered to be hypotensive disease, so the blood pressure of 100/53mmHg belongs to the hypotensive disease. Hypotensive disorders include physiologic and pathologic ones. Physiologic hypotensive disease is in a part of the healthy population where blood pressure measurements meet the diagnostic criteria for hypotension, but there are no conscious symptoms, and there are no abnormalities such as ischemia and hypoxia in the organs, so treatment is usually not necessary. Some of the hypotension is caused by specific medications, and the hypotensive state may improve on its own after lowering the dosage or discontinuing the use of the medication. Pathological hypotension is a low blood pressure phenomenon caused by some pathogenic factors, such as hemorrhage, severe anemia or infection, acute myocardial infarction and other conditions resulting in a sharp drop in blood pressure. It is recommended to go to the cardiology department of the hospital as soon as possible, improve the examination to clarify the cause of the disease, and then treat the cause of the disease, and the blood pressure will gradually return to normal after the cause of the disease is removed.