Long-term sleeplessness can induce cognitive decline, hair loss, organ dysfunction, and anxiety and depression, as follows: 1. Decline in cognitive function: Long-term sleeplessness can induce a decline in cognitive function, as evidenced by a decline in attention, memory, slowness of reaction, judgment, and calculation, which can induce the risk of dementia in the future. 2. Hair loss: Long-term sleeplessness can lead to hair loss. 3. Dysfunction: Long-term sleeplessness can lead to dysfunction of heart function, liver function, etc. 4, induce anxiety and depression: Long-term sleeplessness can induce anxiety and depression, insomnia and anxiety affect each other, long-term anxiety and depression patients who do not receive treatment, the original insomnia will increase the risk of getting anxiety and depression. Therefore, from either perspective, long-term insomnia has a negative impact on the human body and mind, and requires intervention.