Prolonged sleep deprivation can lead to mood disorders, and patients can experience depression and, in severe cases, depressive disorders. Long-term sleep deprivation can also lead to inadequate rest for brain cells, resulting in poor concentration, memory loss, and cognitive impairment as the disease progresses and worsens. Patients who do not sleep for a long time may develop heart disease, such as atrial premature beats and ventricular premature beats, due to arrhythmias caused by not sleeping. Patients who do not sleep for a long time can also develop gastrointestinal disorders, which can be manifested as bloating after eating, indigestion, constipation, etc. Long-term sleep deprivation can lead to symptoms in several organs of the body, so it is important to adjust sleep. Clinically, you can take oral sedative and sleeping drugs, such as eszopiclone, zolpidem tartrate tablets, etc. It is recommended to take them orally under the guidance of a physician.