In clinical treatment, itchy soles of the feet are particularly itchy and the cure needs to be decided according to the specific disease, including the following: a. Tinea pedis, which is caused by fungal infection, can be treated by applying compound snake fat ointment, mixed with luliconazole ointment or griseofulvin ointment, to detoxify, kill insects, and kill fungi. In severe cases, it can be combined with oral itraconazole capsules or terbinafine hydrochloride tablets, combined with Baixian Xia Taje capsules taken orally. Second, palmoplantar pustulosis, the disease is caused by excessive thickening of the plantar area keratin layer, you can apply tazarotene gel, along with hydrocortisone butyrate ointment, or harcinexide ointment glucocorticoid drugs for application, after the application can be combined with oral chlorpheniramine maleate tablets to strengthen the anti-itch, anti-allergy treatment.