Thrombocytopenic purpura is also known as primary immune thrombocytopenia. Treatment includes drug therapy and splenectomy. 1. Drug therapy (1) First-line treatment: these drugs are generally the drugs of choice. Glucocorticoid drugs include prednisone, dexamethasone and so on. Gammaglobulin is generally used in the form of intravenous infusion. It is mainly applicable to the emergency treatment of primary immune thrombocytopenia, patients who cannot tolerate glucocorticoid drug treatment, before pregnancy or delivery, and surgical preparation before splenectomy. (2) Second-line treatment: It is applicable to patients who are not effective in the first-line treatment, and it can also be used for patients who can only be maintained with high-dose glucocorticoid drug treatment. Clinical drugs include thrombopoietic drugs (such as recombinant human thrombopoietin, eltrombopag, romiplostim, etc.), anti-CD20 monoclonal monomer (rituximab), immunosuppressive drugs (such as vincristine, cyclosporine, etc.), danazol, and so on. 2. Splenectomy: It is suitable for patients whose glucocorticoid treatment is ineffective or contraindicated, or whose disease has been prolonged for more than half a year, or whose glucocorticoid maintenance is too large. If the diagnosis of primary immune thrombocytopenia is confirmed, it is recommended to go to the hospital in a timely manner for early and regular treatment. The above drugs should be used under the guidance of a doctor.