What is DC cell and CIK cell therapy?

DC cell and CIK cell therapy both belong to tumor immune cell therapy. 1. DC is the abbreviation of Dendritic Cell, which means dendritic cell. It was discovered by the famous scientist and 2011 Nobel Prize winner in physiology or medicine, Dr. Ralph K. Steinman, in 1973. It was discovered by Dr. Ralph Steinman in 1973. DCs do not kill tumor cells per se, but they can take up, process and present antigens to T cells to initiate specific T cell anti-tumor immune responses. In layman’s terms, DCs deliver information from tumor cells to immune effector cells (tumor-killing T cells) so that the immune effector cells gain the ability to recognize tumors and proliferate, producing specific killing effects on tumor cells. It was found that 1000 DCs can effectively stimulate T cell proliferation, and DCs have strong migration ability. In our clinical practice, we use single nucleated cells in peripheral blood as precursor cells of DC and apply a series of cytokines for induction to obtain high purity DC, then use tumor antigen immune stimulation of DC, which can stimulate specific anti-tumor cell immune response. 2. The full name of CIK cells is Cytokine-induced Killer Cell (CIK). Autologous CIK cells are a heterogeneous population of cells obtained from peripheral blood single nucleus cells in vitro through the induction of multiple cytokines, CIK cells for tumor treatment are characterized by rapid and massive expansion in vitro, broad-spectrum tumor-killing activity, and the ability to kill multi-drug resistant tumor cells.