I. What is DC-CIK cell therapy DC and CIK combination therapy is one of the most mature treatment options for tumor biotherapy. DC (dendritic cells can accurately identify tumor antigens and transmit the information to human immune system, CIK cells are natural tumor killing cells in human immune system, which can kill tumors by playing their own cytotoxicity and secreting cytokines, the combination of the two completes the The combination of the two completes the whole process from identifying the enemy (tumor cells) to destroying them. Another major advantage of combined DC and CIK therapy is the continuous input of immune cells, which can rapidly strengthen the human immune system, improve the quality of life of patients and prolong the survival of tumor patients. At present, the international application of DC-CIK cell therapy for tumors is very mature. Clinical studies have shown that DC-CIK cell therapy plays an important role in removing residual microscopic lesions of tumor patients after surgery, preventing metastasis and recurrence of cancer cells, improving patients’ own immunity and enhancing their physical fitness. It has high killing activity against kidney cancer, breast cancer, gastric cancer, colorectal cancer, ovarian cancer and other cancer cells. DC-CIK cell therapy can effectively target lung cancer, liver cancer, gastric cancer, breast cancer, pancreatic cancer, malignant melanoma, kidney cancer, prostate cancer, ovarian cancer, colon cancer, rectal cancer, primary peritoneal cancer, leukemia, malignant lymphoma (except T lymphoma), skin cancer, oral cancer, laryngeal cancer, nasopharyngeal cancer, tongue cancer, lip cancer, ear tumor, thyroid tumor, benign breast cancer, etc. It has obvious The therapeutic effect of DC-CIK cell therapy is obvious. Advantages of DC-CIK cell therapy program 1.Wide indications: It can effectively treat most solid tumors and eliminate tumor cells that are insensitive to radiotherapy and chemotherapy and metastasis. 2.Safety: Using human body’s own cells to kill tumor cells, no toxic side effects. 3.Persistence: activate the immune system of the body, restore the immune function of the body and kill the tumor cells permanently. 4. Completeness: improve the immune ability of the body and completely remove residual tumor cells and micro metastatic lesions in the body. 5.Targeted: antigen-loaded DC cells can induce immune cells that directly recognize and kill tumor cells, and CIK cells non-specifically kill tumor cells. 6. Comprehensiveness: to rebuild and improve the immune function of the patient’s whole body, to comprehensively identify, search and kill tumor cells, and effectively prevent tumor recurrence and metastasis. Effect of DC-CIK cell therapy 1.Effectively remove residual tumor cells after surgery, prevent tumor recurrence and metastasis, can reduce the early tumor recurrence rate to 30%. 2. Combined use with radiotherapy and chemotherapy can effectively reduce the toxic side effects of radiotherapy and chemotherapy and improve the efficacy of radiotherapy and chemotherapy. 3. For advanced tumor patients who have no chance of surgery and recurrence of metastasis, repeated transplantation of large amount of DC-CIK can rapidly relieve the symptoms of advanced tumor patients, enhance their appetite, improve their sleep, improve their physical condition, and enable them to survive with tumor. V. Suitable groups for DC-CIK cell therapy 1. Various immunogenic tumors, such as lung cancer, gastric cancer, kidney cancer, melanoma, etc. 2.After the removal of the primary focus, the immunity is low and the recovery is slow, so as to prevent tumor recurrence. For example: post-operative gastric cancer, post-operative lung cancer, post-operative liver cancer, etc. 3.Widespread metastasis of tumor which cannot be operated. 4.Tumor patients who are not sensitive to radiotherapy or are worried about the huge side effects of radiotherapy and chemotherapy and are unwilling to undergo radiotherapy and chemotherapy. 5.Patients who need to improve body immunity after conventional treatment (surgery and radiotherapy and chemotherapy). 6.Tumor recurrence prevention after clinical recovery. Our hospital has taken the lead in carrying out this treatment technology in southern Shaanxi, and has treated more than 300 cases, which is at an advanced level in China.