It is recommended to take cephalexin after drinking for more than a week interval. Although many people have a strong metabolizing ability for alcohol and are able to sober up the day after drinking and the alcohol in their body is basically metabolized. However, some people do not metabolize alcohol very well, and it is likely that taking cephalosporin 3-4 days or 5-6 days afterwards may still cause a disulfiram-like reaction. For people who are relieved of alcohol soon after drinking and have finished metabolizing alcohol, it is likely that taking cephalosporin 2-3 days later will not be a problem, but it cannot be accurately guaranteed, so it is still recommended to take cephalosporin more than a week apart. If a bacterial infection does occur and antibiotic treatment should indeed be applied, drugs that do not interact particularly significantly with alcohol can be chosen for treatment, and cephalosporin-based antibiotics are not recommended.