Depression does not directly affect the patient’s life expectancy, but the pessimism associated with depression can lead to suicidal tendencies, which can be life-threatening at any time. Depression is a mental illness characterized by symptoms such as low mood, loss of interest, decreased energy, and generalized fatigue. As a result of mood changes, patients may experience somatic symptoms such as dizziness, fatigue, nausea, and stiffness, which can cause discomfort but generally do not directly affect the patient’s life expectancy. Depressed patients will form a very negative and pessimistic mindset and have strong suicidal thoughts because they have lost interest and confidence in life. Therefore, the suicide rate of depressed patients is relatively high, and they may commit suicide and die at any time. For patients with depression, therapeutic intervention should be carried out as early as possible, while paying attention to supervision and prevention of adverse events.