Don Kyoung Choi from Samsung Medical Center, Korea, published an article in JU 2015 on the study of the effects of different stages of preoperative chronic kidney disease on renal structural reconstruction and renal function changes after radical kidney cancer surgery, mainly to investigate the effects of different stages of preoperative chronic kidney disease (CKD) after radical kidney cancer surgery on patients’ compensatory renal volume enlargement and filtration function The impact of increased filtration function. A retrospective study of 543 patients who underwent radical kidney cancer surgery between 1997 and 2012 was conducted. Patients were classified according to their glomerular filtration rate (GFR). [No chronic kidney disease: GFR ≥ 90 ml/min/1.73m2 (N = 230, 42.4%), chronic kidney disease stage II: 60 ≤ GFR < 90 ml/min/1.73m2 (N = 227, 41.8%), chronic kidney disease stage III: 30 ≤ GFR < 60 ml/min/1.73m2 (N = 86, 15.8%). The volume of the functional kidney was assessed by CT images reviewed 2 months before and up to 1 year after surgery to measure the degree of enlargement of the kidney left behind, and preoperative and postoperative GFR/FRV was used to calculate the degree of hyperfiltration rate. The results showed that for all patients (mean age 56.0 years), the mean preoperative GFR, FRV, and GFR/FRV were 83.2 ml/min/1.73m---2, 8515px3, and 0.25 ml/min/1.73m2/cm3, respectively. there was a statistical difference in the percentage reduction of glomerular filtration rate according to the different stages of CKD (no chronic kidney disease However, there was no statistical difference in the degree of volume thickening of the kidneys left behind (without chronic kidney disease: 18.5%; CKD stage II: 17.3%; CKD stage III: 16.5%; P = 0.250). there was a statistical zen in the change in GFR/FRV ( without chronic kidney disease: 18.5%; CKD stage II: 20.1%; CKD stage III: 45.9%; P<0.001). Factors associated with higher than normal GFR / FRV were body mass index (p-value= 0.012), diabetes (p-value= 0.023), hypertension (p-value= 0.015), and CKD stage (p<0.001) This study showed that patients with low preoperative glomerular filtration rate (GFR) had less reduction in postoperative renal function compared to those with high GFR, and had stronger filtration function.