Graves’ disease is also known as toxic diffuse goiter and Graves’ disease; Graves’ disease and Hashimoto’s thyroiditis have certain differences in clinical manifestations, treatment and prognosis. 1. Clinical manifestations: Graves’ disease can have symptoms of thyrotoxicosis such as goiter, proptosis, insomnia, palpitations, shortness of breath, weight loss, fear of heat and excessive sweating, etc. Hashimoto’s thyroiditis can have symptoms of hypothyroidism such as goiter, malaise, lethargy, memory loss, constipation, fear of cold, bradycardia, etc. The treatment of Graves’ disease is very different from that of Hashimoto’s. The treatment of Graves’ disease is very different from that of Graves’ disease. 2. Treatment: Graves’ disease is treated with medications such as methimazole, propoxythiopyrimidine and other antithyroid drugs, propranolol and other beta-blockers, radioactive iodine therapy, and surgery; Hashimoto’s thyroiditis is treated with medications such as levothyroxine sodium tablets, and surgery can be considered when a goiter occurs that produces symptoms of compression. 3. Prognosis: Graves’ disease can be cured, but it may recur after cure; while Hashimoto’s thyroiditis cannot be completely cured, and when accompanied by hypothyroidism, lifelong medication is usually needed. Patients with suspected Graves’ disease or Hashimoto’s thyroiditis symptoms should go to the hospital in time, and those who are diagnosed with Graves’ disease or Hashimoto’s thyroiditis should actively cooperate with the doctor for treatment.