There is no way to remove scleroderma, which is categorized into limited scleroderma and systemic scleroderma. The prognosis for most patients with limited scleroderma is very good, at most, localized skin atrophy and scarring will remain, and early symptomatic treatment such as glucocorticoid ointment or tacrolimus ointment can be applied. Systemic scleroderma, patients should be early to the rheumatology department, in the early stage of the disease, that is, the skin edema stage, can apply a small dose of glucocorticoids to prevent the skin from fibrosis, can prevent new skin lesions, but also can help to prevent the damage of important organs. In patients with renal or lung damage, high doses of glucocorticoids and immunosuppressive drugs may be indicated, depending on the severity of the lesions, and vasodilators may be indicated for Raynaud’s phenomenon.