Whether 80 years old can undergo cystectomy is mainly related to the condition of the disease and the physical condition; if the lesion is in the early stage and the patient’s physical condition is good, the patient can undergo cystectomy; if the lesion has already had extensive invasion of the surrounding tissues and metastasis, the patient’s physical tolerance is poor, and the patient cannot be operated. Total cystectomy is mainly for bladder tumors, the tumor has no obvious invasion to the surrounding tissues in the early stage, and the patient’s physical condition is good, and the patient’s tolerance to the surgery is strong, so the total cystectomy can be performed for radical resection. When the lesion enters the advanced stage, there is no more indication for surgery, or the patient’s own physical condition is obviously deviated and can not tolerate the surgery, accordingly, the total excision surgery can not be done, and only palliative treatment can be chosen. After the discovery of bladder lesions, you need to be admitted to the hospital in a timely manner to confirm the diagnosis of the specific condition, under the guidance of the clinician for standardized treatment, to avoid causing delays in the condition.