Upper dryness and lower cold, should be the upper heat and lower cold evidence (the upper part of the heat, the lower part of the cold), common fever and sweating, swollen and painful gums, mouth and tongue sores, dry throat and coughing, upset and irritable, but below the waist of the fear of cold, knee soreness and weakness, cold pain in the abdomen, and women may experience menstrual cramps and other symptoms. It is recommended to seek timely medical treatment for the above symptoms. Upper heat and lower cold are mostly caused by prolonged illness and physical weakness, improper use of medication, poor diet, frequent late nights and other factors leading to the depression of heat in the upper Jiao and cold in the lower Jiao. The treatment should clear the heat in the upper Jiao and warm the cold in the lower Jiao. Depending on the specific symptoms, Wu Mei Pills or Jiaotai Pills can be chosen for treatment. The efficacy of Wu Mei Pill is to harmonize the liver and regulate the stomach, clearing the upper and warming the lower Jiao. It consists of Wu Mei to generate body fluid, Huajiao, Xinxin, Ginger and Radix et Rhizoma Polygoni Multiflori to warm the inner Jiao, Angelica Sinensis to nourish the blood, Cinnamon Branches to warm menstruation and open up the veins, Huang Lian and Huang Bai to clear heat and ginseng to replenish vital energy. Pregnant women are forbidden to take this product. Jiaotai Pill is mainly used for the treatment of panic and insomnia, easy irritability, excessive urination, fear of cold, cold hands and feet caused by incompatibility between the heart and kidney (heart fire and kidney yin deficiency, dysfunction of the physiological functions of the heart and kidney). The constituent drugs of this medicine are Rhizoma Coptidis, which clears heat, and Cinnamomum Cassia, which warms the yang and induces the fire to return to the source (inhibiting the rise of fire evil in the kidneys). This product is not recommended for people with weak spleen and stomach. Specialized individuals should take this product under the supervision of a physician. For cases of upper heat and lower cold, it is necessary to be diagnosed by a medical practitioner and use the medicine under medical supervision.