Zhenju Antihypertensive Tablet has the following hazards for long-term use: digestive system, urinary system, cardiovascular system, metabolism and nutrition, skin and its accessories: 1. Digestive system: nausea, vomiting, anorexia, abdominal pain, diarrhea or constipation, jaundice, liver function abnormality, drug hepatitis, cholecystitis and so on. 2. Urinary system: urinary frequency, urinary urgency, urinary difficulty, urinary retention, nocturia, hematuria, renal function abnormalities. 3. Cardiovascular system: postural hypotension, low blood pressure, syncope, chest tightness, palpitation, tachycardia, bradycardia, ECG abnormality, heart failure, etc. 4. Metabolism and nutrition: hypokalemia, hyponatremia, hyperuricemia, elevated blood glucose, elevated serum creatine phosphokinase concentration, hypochloremic alkalosis or hypochloremic hypokalemic alkalosis, etc. 5. Skin and its accessories: rash, dermatitis, pruritus, hyperhidrosis, angioneurotic edema, alopecia, etc. The drug not only has an improving effect on the damage of endothelial structure as well as endothelial dependent Gan diastolic function caused by hyperlipidemia, but also has a good anti-hypertensive effect. Clinically the drug is commonly used in the treatment of hypertension. It is contraindicated for those who are allergic to this product; those who are allergic to this product or other sulfonamide-based drugs. Liver and kidney function and water and electrolyte balance should be closely monitored during the use of the drug; driving or machine operation should be avoided during the use of the drug; blood pressure changes should be monitored when adjusting the dosage of the drug or combining with other antihypertensive drugs. If the drug is needed, it should be used under the guidance of a physician; if the patient takes the drug for a long time, he/she should go to the hospital for regular checkups in order to prevent the drug from causing accumulative adverse reactions.