In recent years, the number of patients with cranial defects has gradually increased, especially in recent years, various traffic accidents, production safety accidents, accidental injuries and other events have been frequent, so the number of traumatic cranial defects caused by them has also gradually increased. Cranial repair Cranial defects not only bring a large mental burden to patients, but also require cranial repair because the brain tissue lacks an intact cranial protective barrier and is prone to injury and a series of secondary symptoms. The repair of traumatic cranial defects is gradually gaining the attention of neurosurgeons. Cranial repair is a relatively routine procedure in neurosurgery, the main purpose of which is to solve the problems of lack of effective protection of brain tissue in the defect area, blood supply disorders, abnormal cerebrospinal fluid circulation, and also to solve the problems of shape repair and plastic surgery. It is not good to perform skull repair too early or too late. In the neurosurgical guidelines, for patients with cranial defects due to debridement, generally 3-4 months after the defect, if the defect area reaches 3*3 cm or more, it meets the characteristics of surgery and the patient needs to go to the hospital to be repaired by a specialized surgeon. Cranial bone repair is a common surgery, the implementation of which is not difficult and can be carried out in large hospitals in general. As long as the scalp is cut open, the periosteum is bluntly separated, the bone window is completely exposed, the repair prosthesis is placed in the bone window and adjusted to achieve physiological anatomical reset, and the skin is sutured layer by layer. The results vary greatly depending on the surgical approach taken and the doctor’s expertise. Of course, the material of cranial bone repair is also the most important, the selection of cranial bone repair material has its own standard, the choice of material first requires high biocompatibility, and needs to ensure a certain strength and stiffness at the same time, both to provide strong enough protection, but also to meet the needs of shaping, to achieve the shape repair cosmetic satisfactory effect. Throughout thousands of years of history, our ancestors also kept exploring the cranial repair materials. After a long period of development, the repair materials have become more and more advanced and closer to the standard. From the flannel sheet covering the bone window repair thousands of years ago, to the metal sheet, plexiglass, light apatite and calcium phosphate bone cement, etc., to the titanium mesh material which was widely used clinically in the previous period, it can be said that it has been progressing. But these materials always have such and such problems, and not achieve the very ideal effect. Technological innovation, polyether ether ketone PEEK cranial repair Currently, the new material polyether ether ketone, also known as PEEK material, is widely favored by medical experts, and expert teams use peek material for cranial repair. First of all, PEEK material is very biocompatible, non-reactive, and does not interfere with postoperative medical examinations. In addition, it is comparable to autologous cranial bone in terms of strength, stiffness, elasticity, and thermal insulation, and more importantly it is preoperatively shaped in three dimensions according to the patient’s cranial data.