Sodium and water retention should be seen in a hospital to identify the cause. The most common clinical causes that can cause sodium and water retention are kidney disease, heart disease, liver disease and diseases of endocrine origin. If it is renal disease is seen in chronic nephritis, renal failure, etc. In early stages of renal insufficiency, symptomatic treatment with diuretics can be applied intermittently. Advanced renal failure requires renal replacement therapy, such as hemodialysis, hemofiltration and, if necessary, renal transplantation therapy. In case of sodium and water retention caused by cardiac insufficiency, right heart failure or total heart failure is considered, which needs to be followed by diuretics or hemofiltration treatment after intravenous placement. If the sodium retention is caused by liver failure, plasma exchange should be performed if drug therapy is not good.