Sodium and water retention should be seen in a hospital to identify the cause. The most common causes that can cause sodium and water retention in clinical practice are kidney disease, heart disease, liver disease and diseases of endocrine origin. If it is a kidney disease, it can be seen in chronic nephritis, renal insufficiency, renal failure, etc. In the early stage of renal insufficiency, symptomatic treatment with diuretics can be applied intermittently. Advanced renal function requires renal replacement therapy, such as hemodialysis, hemofiltration and, if necessary, renal transplantation therapy. In case of sodium and water retention caused by cardiac insufficiency, right heart failure or total heart failure is considered, which needs to be followed by diuretics or hemofiltration treatment after intravenous placement. If sodium and water retention is caused by liver failure, plasma replacement should be performed.