Lumbar puncture refers to lumbar puncture, which is a common examination operation in neurology and is commonly used for the diagnosis of infectious diseases of the central nervous system, subarachnoid hemorrhage, and other immune inflammatory diseases. The lumbar puncture itself only costs about$80-100 for the operation, but the lumbar puncture requires a cerebrospinal fluid examination, and the associated tests, depending on the item, are charged differently. Routine tests, including cerebrospinal fluid routine, cerebrospinal fluid biochemistry, and cerebrospinal fluid bacterial culture, cost roughly between$200 and$300. However, for special items, such as water channel protein 4 antibodies for optic neuromyelitis optica spectrum disease, and oligoclonal zone banding for multiple sclerosis, the cost is about$2,000. There are also special cerebrospinal fluid cytology tests and immunohistochemistry tests, the price of which varies depending on the specific test.