How to deal with 80% blockage of the rotary branch depends on the location of the blockage. The distal part can be treated with oral medication, while the proximal and middle parts can be implanted with stents. The 80% blockage of the rotary branch is a serious stenosis, which can lead to a reduction in blood supply to the heart muscle, and patients can experience angina symptoms, and even have the risk of acute myocardial infarction. Coronary angiography can be used to visualize the location of the stenosis. The distal section of the circumflex branch is relatively thin, and if the stenosis is 80%, it can be treated with oral medication, such as aspirin, atorvastatin, isosorbide nitrate and other drugs. If the stenosis is in the proximal middle segment and there are symptoms of angina, a stent can be implanted, and then continue to give antiplatelet and lipid-lowering treatment. For patients with gyratory branch stenosis, the severity of the condition should be evaluated under the guidance of a physician to develop a specific treatment plan.