An occupying spinal cord lesion is generally a tumor in the spinal cord that compresses the spinal cord and has an occupying effect, that is, it occupies the position of the normal spinal cord, so it is called an occupying lesion. Most of them are malignant tumors, such as the common subdural chordomas and nerve sheath tumors, and epidural metastases, including vertebral osteomas, and some chordomas, which may compress the spinal cord; there are also gliomas and cholesteatomas in the spinal cord itself, which are called occupying lesions. These are called occupational lesions. Occupational lesions should account for a large proportion of spinal cord lesions and require very aggressive treatment. Benign tumors such as spinal meningiomas and nerve sheath tumors, if surgically removed, can be completely cured without causing any other effects on the patient. For malignant tumors in the spinal cord or epidural malignant tumors, the corresponding treatment can also prolong the patient’s survival and improve the patient’s quality of life after the pathology is clarified through surgery. Therefore, occupying lesions should be taken seriously and treated actively.