Mycoplasma infection in children is a common pathogenic bacterial infection in pediatrics. Characterized by mycoplasma infection, pediatric fever, cough, cough sputum as the main clinical manifestations. Mycoplasma infections are usually treated with macrolide antibiotics, azithromycin and erythromycin as the main drugs. Mycoplasma infection medication is usually the course of the disease is about 3 weeks, the specific course of medication such as azithromycin medication is required to apply 3 days after stopping for 4 days, and then 3 days, to reach half a month of a process. According to the child’s condition later to further adjust the medication. Mycoplasma drugs usually stimulate the pediatric gastrointestinal, can cause nausea, vomiting, diarrhea and a series of symptoms, so the application of mycoplasma drugs for children with poor gastrointestinal function, must pay attention to 1 hour after the meal and then orally, to avoid the stimulation of the drug caused by vomiting and other gastrointestinal tract unwanted complications, and at the same time during the disease, it is desirable to be light, easy to digest the diet is the main.