Two-year-old baby wakes up easily in the middle of the night, there are usually the following situations: First, the most common is because the child’s diet has a bias or malnutrition, resulting in the child’s vitamin D deficiency, intestinal calcium absorption is reduced, nerve excitability increases, easy to wake up from sleep, the main thing in this case is to supplement vitamin D3, appropriate calcium, more sun, while adjusting the diet to give adequate nutritional balanced food. Second, we should pay attention to some children may be due to the problem of trace elements, such as zinc deficiency, iron deficiency children, or lead exceeds the standard of the child, zinc deficiency, iron deficiency can usually be supplemented with zinc, iron, lead exceeds the standard of the lead can be expelled from the lead treatment. Third, there are also some children who may have neurological excitability of the underlying disease, such as a history of epilepsy, or birth asphyxia, hypoxia history, usually should see the pediatric neurology clinic, do the appropriate examination, evaluation and treatment.