Most parents deliberately hide their child’s true condition from them in the beginning. As they get older, children and adolescents with epilepsy become more eager to learn about the disease. Clinicians and parents should be proactive in educating them about epilepsy and the impact of the disease on their future. They should be taught how to cope with seizures in their daily lives, protect their lives, and diffuse the fear associated with seizures. Parents should focus on training their children in self-management of the disease (keeping a log, taking medication, regular follow-up visits, etc.), basic independent living skills, and healthy lifestyles including coping with stress and pressure, getting enough sleep, and emotional adjustment. Children and adolescents with epilepsy are often affected in school performance and academic achievement due to the potential and long-term risks of attention, thinking skills, and cognitive impairment associated with childhood seizures. Parents should work with teachers to help children with epilepsy with their learning tasks according to their condition and characteristics. Some findings suggest that children and adolescents with epilepsy are physically better than their peers with other chronic diseases, but psychosocially, they have a greater sense of isolation, social isolation, teasing and shame, and poorer socialization, with females having poorer socialization than males. Recent studies of children with new-onset epilepsy have shown that psychiatric disorders, cognitive deficits, and behavioral problems can appear early in the disease, even at the onset of epileptic disorders. Therefore, parents should pay attention to the emotional and psychiatric aspects of their children and try to develop their social skills. Family-related psychiatric factors, such as greater family stress, fewer family resources, and negative attitudes of family members toward epilepsy, can have a great impact on the child. Parents should make appropriate family adjustments in this regard and give the child a warm and harmonious family environment. However, excessive parental worry and protection may lead to over-dependence of the child, resulting in a lack of independent living ability in adulthood. In addition to education within the family, school staff should also strengthen education in epilepsy knowledge so that they can also educate other normal children and adolescents, which will help to eliminate the child’s sense of social isolation. There is a high demand for recreation and sports during childhood and adolescence, and they need to be helped and accompanied to participate in some low-risk recreation and sports programs, such as camping, jogging and walking, etc. Cultivation of hobbies is also beneficial to physical and mental health. Attention should be paid to taking protective measures to prevent accidental injuries. In addition, do not deliberately avoid or deny the existence of some special sensitive problems in adolescence, such as sex, early love, drinking, etc.. If necessary, they should be frankly communicated and informed of the relationship with seizures to help them make rational decisions.