The main insulin resistance detection methods commonly used in the clinic are glucose clamp technique, tiny model method, glucose tolerance test with simultaneous measurement of insulin release curve, fasting insulin and so on. 1. Glucose clamp technique: also known as glucose clamp test, is a method to quantitatively detect insulin secretion and insulin resistance. This method has become the “gold standard” for assessing the sensitivity of pancreatic β-cells to insulin. 2. Tiny model method: It is a simple and easy method, but the result is not as accurate as clamp method. It simulates the relationship between blood glucose and insulin metabolism in human body through computer, so as to reflect the degree of insulin resistance. 3. Glucose tolerance test with simultaneous measurement of insulin release curve: Oral glucose tolerance test and islet function test are required, after which the degree of insulin resistance is assessed. 4. Fasting insulin: It is the simplest indicator to reflect the operation of insulin resistance. Insulin resistance may exist in diabetic patients, and the test of insulin resistance is used to initially understand the function of the pancreas, so as to determine the severity of diabetes mellitus. The test for insulin resistance should be conducted under the guidance of a doctor, who will interpret the test and find abnormalities for timely treatment.