The appearance of neonatal heat rash is considered to be related to the underdevelopment of sweat ducts and overheating of the environment, which can be relieved by room temperature regulation, local treatment and drug intervention. 1. Room temperature regulation: After the appearance of neonatal heat rash, it is necessary to regulate the indoor temperature by means of fans or air conditioners, so as to cool down the skin and improve the symptoms of neonates. 2. Local treatment: If the symptoms of heat rash are more serious, you can wipe the lesions with warm water, which can relieve pain and stop itching. If necessary, saline cold compresses can be used on the lesion area. 3. Pharmacological intervention: newborn fever rash symptoms, but also through the external use of glycerite lotion coated, to achieve astringent and anti-itching effect. If accompanied by secondary bacterial infection, if necessary, also need to apply fusidic acid, mupirocin ointment treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication.