Multiple small lymph nodes in the hilar and retroperitoneal area may be a physiological phenomenon or a symptomatic manifestation of certain diseases, such as mesenteric lymphadenitis and tumors, etc., and the cause of the disease should be identified by timely consultation. 1. Under normal circumstances, the lymph nodes in the hilar and retroperitoneal areas are small in size and are not visualized on imaging. If small lymph nodes can be found on imaging, the lymph nodes may be physiologically or pathologically enlarged. Physiologic enlargement usually requires no treatment and observation is sufficient. 2. If there are recent symptoms of abdominal pain, bloating, belching and other discomforts, it means that there may be inflammation in the abdominal cavity. The lymphatic fluid from the infected area can drain to the hilar and retroperitoneal lymph nodes, causing secondary inflammation of the lymph nodes and mesenteric lymphadenitis. 3. If there are symptoms of loss of appetite, emaciation and weight loss recently, there may be tumors in the abdominal cavity, and the tumors have metastasized to the lymph nodes in the hepatoportal area and retroperitoneum, making them enlarged and hyperplastic. It is recommended to go to the hospital, improve the examination, and carry out the treatment under the doctor’s guidance.