Myopia of 400 degrees cannot be reversed. Patients can correct myopia and improve their vision by wearing framed glasses and keratoplasty lenses, and can also be corrected by refractive surgery in adulthood. Myopia 400 degrees, belongs to moderate myopia, patients will have a significant decrease in naked eye vision, can be corrected by the following methods to correct vision. 1. Framed glasses: Framed glasses are a safe and commonly used method of vision correction, easy to remove and wear, and relatively inexpensive. 2. Keratoplasty lenses: Keratoplasty lenses are a kind of rigid high oxygen permeable corneal contact lenses, which can be worn at night and removed during the day, and can maintain good naked eye vision during the day, but there are certain indications and contraindications. 3. Refractive surgery: If myopic patients reach the age of 18 years old, myopia is stable, 400 degree myopia patients can correct myopia through refractive surgery, such as excimer laser correction, semi-femtosecond laser correction, full-femtosecond laser correction, etc., to improve vision. It is recommended that myopic patients seek timely medical consultation to assess their condition and follow the doctor’s instructions for treatment.