Jisheng Kidney Qi Wan is based on the formula of Liu Wei Di Huang Wan with the addition of several herbs, like Niubizi, Radix et Rhizoma, Psyllium and Cinnamon, which enhance the effect of warming Yang and diuretic, so its effect changes to warming the kidneys and promoting water retention, diuresis and decongestion. It can be mainly used to treat the symptoms of soreness and heaviness of the waist and knees, unfavorable urination, phlegm and cough caused by kidney deficiency and edema. Modern research on Jisheng Renqi Wan has a protective effect on the kidneys, and it can also reduce urinary protein caused by nephritis, and can reduce the level of serum creatinine and urea nitrogen. However, because Jisheng Renqi Pills contains Radix et Rhizoma Polygonati and Radix Bupleuri, it is contraindicated in women during pregnancy. It is also not advisable to take it together with preparations or tonics containing the above drug ingredients because of the presence of eighteen transitions in Radix et Rhizoma, Semen, Psidium Guajava, Phellodendron, Bupleurum, and Bletilla.