Pregnant women with eczema that itches so much at night that they can’t sleep can be treated with topical and, if necessary, oral medications. Eczema of pregnancy manifests as papules, papules, blisters, peeling skin, etc., which can be accompanied by severe itching. 1. Topical medication: if the patient’s skin is not eroded, oozing, can be used externally with glycerine lotion to stop itching; if there is a large amount of oozing, you can choose boric acid solution for cold wet compresses. If the disease is serious, you can choose to use weak glucocorticosteroids. 2. Oral medication: when the condition is serious, under the weighing of the pros and cons of the situation, if necessary, oral loratadine and other antihistamine treatment. All of the above drugs need to be used under the guidance of a professional doctor, not blindly self-medication, in order to avoid adverse effects. Pregnant women with eczema itchy at night can not sleep, do not scratch the affected area, can be relieved by patting the affected area, and promptly go to the hospital for treatment.