It is important not to be careless after cranial defects occur. It is found that long-term cranial defects will have a great impact on both the appearance and psychology of people. First of all, it will cause unsightly and asymmetrical skull appearance, and even cranial collapse or bulging, which will make patients have a deep sense of inferiority; secondly, without the protection of hard shell, the brain tissue will be easily injured by external tissues; in addition, cranial defect will cause changes in the intracranial environment and unstable intracranial pressure, which will affect the normal cerebrospinal fluid circulation and blood circulation, thus affecting the normal neurological function. In principle, as a routine surgery in neurosurgery, skull repair has mature technology and high safety, and patients basically will not have complications after surgery. However, from the results of clinical practice, titanium mesh skull repair still has many problems. It uses metallic titanium as the implant material, which is highly susceptible to postoperative problems such as rejection infection; in addition, it uses a covering repair, which is prone to cutting injury or abrasion to the scalp and material exposure. Our team’s polyether ether ketone PEEK cranioplasty procedure has been widely recognized and praised by patients. peek is used as the implant material and is an embedded repair, which avoids many of the shortcomings of titanium mesh cranioplasty. In addition, this surgery has four technical innovations after studying hundreds of cases and uses unique material thickness and mesh aperture design as well as unique intraoperative tissue separation and repositioning techniques to further improve aesthetics. Many patients with cranial defects are concerned about the price of PEEK cranial repair materials and reimbursement. Generally speaking, cranial repair surgery is covered by medical insurance, but the specific reimbursement rate is determined by the policy of the participating country.