Drinking alcohol after taking medication can cause a variety of uncomfortable reactions in the body, generally seen in the following cases: 1, cephalosporin antibiotics: cephalosporin antibiotics can inhibit the metabolism of alcohol in the liver, inducing a disulfiram-like reaction. Disulfiram-like reaction is a more serious reaction, mainly manifested as skin flushing, dizziness, fever, panic and shortness of breath, or hypotensive shock. Some patients can also be life-threatening, so do not drink alcohol after taking cephalosporin antibiotics; 2, antihypertensive drugs, hypoglycemic drugs: alcohol can increase the adverse effects of drugs or increase the efficacy of drugs, which leads to discomfort in the patient’s body. For example, alcohol has the effect of dilating blood vessels and lowering blood sugar, which can increase the antihypertensive and hypoglycemic effects of antihypertensive drugs and hypoglycemic drugs, and cause patients to experience hypotension and hypoglycemia; 3, non-steroidal antipyretic and analgesic drugs: it can aggravate the stimulation of the drug on the stomach, induce bleeding of the gastric mucous membrane, and aggravate the damage of the non-steroidal antipyretic drugs to the liver. Alcohol can produce damage to the liver, and non-steroidal antipyretic drugs, also have an effect on the liver, under this dual role, liver damage can occur.