Diagnosis of multiple sclerosis in 22-year-old with limb weakness and speech impediment; comprehensive treatment helps recovery

(Disclaimer: This article is only for scientific purposes, in order to protect the privacy of patients, the relevant information in the following content has been processed) Abstract: The patient in this case, self-reported that he was diagnosed with multiple sclerosis 2 years ago, and 3 months ago, there was weakness of the right side of the limbs accompanied by speech clumsiness, unsteady walking, and difficulty in walking a straight line, and recently there was weakness of the limbs and speech clumsiness so he came to the hospital, and intracranial MRI was performed, and the diagnosis was multiple sclerosis, which is a type of central nervous system disease. He was diagnosed with multiple sclerosis, which is a disease of the central nervous system. After the patient was given medication and psychological counseling, the symptoms of weakness and clumsiness were relieved, and the patient was discharged from the hospital. Basic information] Female, 22 years old [Type of disease] Multiple sclerosis [Hospital] The Second Affiliated Hospital of Harbin Medical University [Date of consultation] February 2022 [Treatment plan] Medication (Ginkgoloderma Injection + Inosine Sodium Chloride Injection + Vitamin B1 tablets + Vitamin B12 tablets + Methylprednisolone tablets) + Psychological counseling [Period of treatment] Inpatient treatment for 10 days, outpatient follow-up after 1 month. Treatment effect] Limb weakness and speech clumsiness were relieved, and the patient was successfully discharged from the hospital. I. Initial consultation The patient was a college student, who developed right limb weakness with speech clumsiness 3 months ago, and was able to lift his upper limbs and walk his lower limbs, but his walking was unsteady and difficult to walk in a straight line. After detailed questioning, the patient was diagnosed with multiple sclerosis 2 years ago, and was hospitalized several times in the past 2 years due to fluctuations in his condition, which seriously affected his study and life, and caused him to suffer from mental anxiety and nervousness, and his personality changed, making him more withdrawn and socially withdrawn; he suffered from recurrent headaches, blurred vision, and numbness of the limbs during the period, and was treated without any after-effects. On this occasion, the patient came to the hospital because of weakness of limbs and clumsy speech. The patient’s own head CT results showed bilateral multiple ischemic foci, and the patient was then admitted to the hospital. Second, the treatment process The patient was admitted to the hospital to improve the head magnetic resonance, lumbar puncture and other examinations. Physical examination showed: general condition was good; specialized examination: mental clarity, dysarthria, bilateral pupil light reflexes existed and moved freely, no facial paralysis, tongue extension centered, no neck strength, right limb muscle strength grade 4; head magnetic resonance examination showed: multiple abnormal signals in the brain (including the brainstem), considering demyelinating changes. Lumbar puncture examination showed: cerebrospinal fluid sugar 2.55mmol/L, cerebrospinal fluid chloride 124.0mmol/L, cerebrospinal fluid pressure 210mmH2O, cerebrospinal fluid albumin 552mg/L, and cerebrospinal fluid cell count 5, and the combined clinical results finally diagnosed multiple sclerosis. Subsequently, the patient was given ginkgoloderma injection to improve circulation; inosine sodium chloride injection to improve energy metabolism; vitamin B1 tablets, vitamin B12 tablets for nerve nutrition; methylprednisolone tablets for hormone shock treatment, and then gradually reduced the amount of hormone shock treatment, and at the same time, the patient was given psychological counseling and comfort. Third, the therapeutic effect after giving patients methylprednisolone high-dose hormone shock, patients may appear at night insomnia phenomenon, give psychological comfort and oral sleeping pills can basically improve. However, through the combination of the above drugs, the patient’s limb weakness and speech clumsiness and other symptoms can be significantly relieved, the right side of the limb muscle strength relief, the mental outlook is better than before, the quality of sleep is effectively improved, the patient was discharged from the hospital in 10 days, and asked the patient to be discharged from the static dose of methylprednisolone to oral, the need for slow and gradual reduction of dosage, and one month after the outpatient follow up. Precautions It is gratifying that the patient’s condition has improved significantly after the combined treatment with drugs, and the quality of sleep has been improved. However, after discharge, the patient still needs to pay attention to the following matters: 1, it is recommended that the patient should pay attention to the observation of the recovery of the condition after discharge, follow the doctor’s instructions to take the medication on time and in accordance with the dosage, and if other uncomfortable symptoms, or weakness of the limbs reoccur, consult a doctor in time to avoid delaying the condition; 2, life, eat a light diet, keep a reasonable and healthy eating habits, avoid eating too much spicy and stimulating food; maintain a positive life habit; Appropriate physical activities to improve their physical quality and enhance resistance. V. Personal insights Multiple sclerosis clinical types are different, and the difference in the course of the disease is also very large, but the vast majority of the prognosis is optimistic, generally will not affect the life expectancy, only a very small number of rapid progression of the disease, may affect the survival time. Relapses are most likely to occur in the first year of disease, and relapses and severe disability are likely within the first 5 years. Indicators of a poor prognosis may be a progressive course after the onset of the disease; the presence of motor and cerebellar signs; short intervals between the first two relapses; and poor recovery from relapses. However, with early detection and treatment, the disease can be effectively relieved and the prognosis is good. As in this case, the discomfort was effectively relieved and disappeared under the combined treatment of drugs. Therefore, once the limb discomfort occurs, we must consult the doctor in time to avoid delaying the condition.