Thrombocytopenia when you have a cold may be caused by infection, or it may be caused by therapeutic drugs, or it may be caused by a combination of hematologic disorders, so you should consult a doctor in time to find out the cause of the disease. 1. Infectious factors: colds generally refer to upper respiratory tract infections, common pathogens for viruses, may also be caused by bacteria. In the process of infection, some pathogens may lead to a decrease in platelets. In addition, patients with colds may have fever, which can also lead to non-immune platelet depletion, usually after the condition improves, platelets can recover on their own. 2. Drugs: In the treatment of cold and flu, if accompanied by bacterial infection, antibiotic treatment is often used, such as amoxicillin, levofloxacin, etc. These drugs may cause platelet reduction. These drugs may lead to a decrease in platelets, generally need to stop or change the drug treatment. 3. Blood disease factors: if the cold patients combined with blood system diseases, such as leukemia, idiopathic thrombocytopenic purpura, etc. can also lead to a decrease in platelets, usually the degree of thrombocytopenia is more serious, the need for timely medical treatment, bone marrow aspiration examination. Thrombocytopenia in cold and flu, should consult the doctor in time, the doctor according to the specific problems of specific analysis, judgment, if necessary, targeted treatment.