1.Brain metastasis of lung cancer Brain metastasis is a more common distant metastasis of lung cancer, often accompanied by serious symptoms and signs, and is one of the main causes of death of lung cancer patients, which should be treated clinically as a tumor emergency. Unexplained headache, vomiting, visual disturbance and personality changes in lung cancer patients may be caused by intracranial hypertension or brain nerve damage caused by lung cancer metastasis to the brain. Brain metastasis is commonly seen in small cell lung cancer and adenocarcinoma. Treatment should be to activate blood circulation, remove phlegm, and activate the meridians, and the medicine should be Dan Shen, Di Long, Centipede, Poria and Hooked vine. 2.Bone metastasis of lung cancer Bone is a common site of distant metastasis of lung cancer, about 20-40% of lung cancer patients have bone metastasis with clinical metastatic symptoms. The most common metastasis sites are: vertebrae, pelvis, femur and iliac bone. Most of lung cancer bone metastases are osteolytic, and osteogenic is rare. The treatment is to tonify the kidney and strengthen the bone, activate blood circulation and relieve pain. 3.Lung and liver metastasis Liver is also a common metastatic site of lung cancer, about 28-33% of lung cancer has liver metastasis. Liver metastasis refers to the invasion of primary lung cancer cells into the liver through blood circulation after they are shed and grow in the liver, and liver metastasis can be single or multiple nodal metastases. The most common symptoms are pain in the liver area, persistent distension and pain, which may be accompanied by loss of appetite, indigestion and other signs of impaired liver function. The treatment is easy to dredge the liver and bile, remove blood stasis and relieve pain, with medicines such as Chai Hu, Yu Jin, Xiang Shen, Dan Shen, Curcuma longa and Turtle Nail. 4.Malignant pleural effusion Lung cancer with pleural effusion is often caused by cancer cells planted in the thoracic cavity, which is especially likely to occur in female adenocarcinoma patients. In recent years, the proportion of adenocarcinoma in non-small cell lung cancer is gradually increasing, thus the number of patients with pleural effusion is also increasing. In Chinese medicine, the treatment should be to broaden the chest, regulate the qi and promote the water, and the medicine should include Guahu Psidium, Scapularia, Jujube, Poria and Poria.