The most direct meaning of bone marrow lesion is a lesion of the bone marrow in the human skeleton, such as inflammation of the bone marrow called osteomyelitis, tumors of the bone marrow called myeloma, ischemic necrosis of the bone marrow or hematopoietic disorders of the bone marrow, all of which are types of lesions that can occur in the bone marrow. Among orthopedic patients, the most common is osteomyelitis. Osteomyelitis is an inflammatory change of the bone marrow caused by the local infection of bacteria to the periosteum through soft tissues, which invades the bone marrow of the human body. Myeloma multiforme is a common malignant tumor, usually seen in middle-aged and elderly people, with more male patients than female patients, and the most obvious symptom is the early localized pain in the bones.