Chemotherapy is not always necessary after total bladder cancer excision. If a patient has undergone total bladder cancer excision, it means that there must be muscle-infiltrating uroepithelial carcinoma of the bladder, otherwise radical electrodesis of this bladder is sufficient. Since there is muscle-infiltrating uroepithelial carcinoma of the bladder, it means that the tumor has some risk of metastasis, depending on the postoperative pathology. If the postoperative pathology suggests lymph node metastasis, adjuvant radiotherapy is recommended, as there is clear evidence that it may be able to prolong the patient’s survival. If there are no lymph node metastases, the need for chemotherapy is currently controversial in cases of early staging. In most cases as superficial mucosal bladder cancer with no lymph node metastasis, chemotherapy is only recommended as level III, which means that it is not always necessary to do it, it may have some benefit, but in this case of well-differentiated type with low risk factors, it is acceptable not to do it.